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This article takes a closer look at the exact biochemical interconnections within the methylation cycle in a way that is easy to read and understand

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This event is regulated by the Bcl-2 protein family hierarchy:Anti-apoptotic guardians (Bcl-2, Bcl-xL), Pro-apoptotic effectors (Bax, Bak) and BH3-only sensors (Bim, Bid, Puma) (Yang et al., 1997